THE BAF COMPLEX IN DEVELOPMENT AND DISEASE

The BAF complex in development and disease

Abstract The ATP-dependent chromatin remodelling complex BAF (= mammalian SWI/SNF complex) is crucial for the regulation of gene expression and differentiation.In the course of evolution from yeast to mammals, the BAF complex evolved an immense complexity with a high number of subunits encoded by gene families.In this way, tissue-specific BAF funct

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The Hedgehog signal transducer Smoothened and microRNA-326: pathogenesis and regulation of drug resistance in pediatric B-cell acute lymphoblastic leukemia

Zahra Sheybani, Soheila Rahgozar, Elaheh Sadat GhodousiDepartment of Biology, Faculty of Science, University of Isfahan, Isfahan, IranPurpose: Multidrug resistance (MDR) and the subsequent disease relapse are the major causes of childhood acute lymphoblastic leukemia (ALL) related death.The Hedgehog (Hh) signaling pathway can contribute to cancer M

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Extent of dispensing prescription-only medications without a prescription in community drug retail outlets in Addis Ababa, Ethiopia: a simulated-patient study

Daniel Asfaw Erku,1 Abebe Basazn Mekuria,2 Abdrrahman Shemsu Surur,1 Begashaw Melaku Gebresillassie3 The Influence of Empathy and Consumer Forgiveness on the Service Recovery Effect of Online Shopping 1Department of Pharmaceutical Chemistry, 2Department of Pharmacology, 3Department of Clinical Pharmacy, School of Pharmacy, University of Gondar, Gon

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